Some studies suggest that metformin may have risk factors that go beyond common side effects. This condition causes a buildup of lactic acid in the blood and can potentially be fatal. Having any of these conditions and taking metformin may cause metformin to be less effective or cause additional health complications, such as lactic acidosis. People with blood problems, kidney problems, kidney disease, liver disease, or breathing problems should be cautious of taking metformin. Anyone with congestive heart failure, compromised kidney function, poor liver function, or diabetic ketoacidosis should not take metformin. People with certain health conditions have an increased risk of experiencing side effects from taking metformin. For adults over the age of 80, metformin is prescribed with caution on a case-by-case basis. It’s generally considered okay for children and adults with type 2 diabetes or prediabetes, as long as a doctor approves it, but dosages will vary. Metformin is not the right medication for people with type 1 diabetes. He or she will give you advice on what to do next, and may tell you to stop taking metformin. If you’re experiencing serious side effects from taking metformin, it’s best to call your doctor immediately. Drinking excessive amounts of alcohol while on metformin can significantly increase the risk of getting lactic acidosis. Lactic acidosis can cause serious side effects and almost always requires hospitalization. Taking metformin may cause a serious condition called lactic acidosis, which is a buildup of lactic acid in the bloodstream. You should seek immediate medical attention if you believe you’re experiencing an allergic reaction. Signs of an allergic reaction include difficulty breathing, swelling of the face or hands, and a skin rash. It’s often necessary for people taking metformin to get regular blood tests to check their vitamin B12 levels.Īlthough it’s rare, metformin may cause allergic reactions. Metformin can affect the body’s ability to absorb vitamin B12 and cause a vitamin B12 deficiency. Taking metformin for extended amounts of time may result in long-term side effects. ![]() If you experience any of the following, consult with a healthcare professional right away: Some serious side effects caused by metformin are dangerous and require immediate medical attention. Metformin is associated with some severe, long-term side effects. Some metformin side effects may go unnoticed, so regular checkups are essential. Most people take metformin for long periods of time, so if side effects don’t go away, they could potentially cause long-term damage. For others, side effects may linger or become worse. For some people, side effects will go away soon after their body adjusts to the medication. Side effects may start when you first start taking metformin. While it can cause weight loss by changing the way the body stores fat, this doesn’t mean that everyone who takes the drug will lose weight, or that you should use it to lose weight. These are some of the most common metformin side effects:Ī common concern about metformin is that it causes weight loss. As with any medication, there are always possible risks. ![]() Learning about the potential side effects of metformin is just as important as learning about the benefits. This medication helps normalize insulin levels and may improve fertility. Metformin can also be prescribed off-label to treat polycystic ovary syndrome ( PCOS ), a condition that can cause elevated insulin levels that increases risk for diabetes. ![]() It is also believed that metformin increases insulin sensitivity, which helps with lowering glucose levels. Metformin works by slowing the release of glucose from the liver and by slowing the body’s absorption of glucose, both of which help lower blood sugar levels. People with type 2 diabetes or prediabetes have hyperglycemia (high blood sugar). ![]() Type 2 diabetes is caused by insulin resistance or decreased insulin sensitivity, which means that the body doesn’t properly respond to insulin. Metformin is most commonly prescribed to help people with type 2 diabetes.
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